The conventional fabrication process of 32P-based applicators involves dripping a 32P solution onto filter paper that conforms to the shape of the lesion, followed by drying. However, this approach has several critical drawbacks: (1) it is a time-consuming process, (2) non-uniform radionuclide distribution due to random droplet placement, which can result in localized excessive or insufficient dosage, (3) up to 50% loss of the 32P radionuclide during the drying process, and the generation of radioactive aerosols that pose a risk to health.
32P敷贴器传统制备工艺缺陷解析：如何解决核素分布不均与安全风险？
本文深入分析32P敷贴器传统滤纸滴注制备工艺的三大核心缺陷：耗时冗长、核素分布不均导致剂量失控、干燥过程高达50%的核素损失及放射性气溶胶危害，提供基于现代技术的工艺优化路径与安全解决方案。
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