阿尔茨海默病如何诊断？β-淀粉样蛋白与tau蛋白病理机制详解

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, accounting for approximately 60% to 80% of all dementia cases. Clinically, it manifests as memory impairment and cognitive dysfunction. The typical pathological features primarily include the accumulation of β-amyloid (Aβ) outside neurons and the abnormal aggregation of tau protein within neurons, accompanied by neuronal death, brain tissue damage, atrophy, and inflammatory responses. Currently, there are no proven effective methods for preventing or curing Alzheimer's disease.