丙烯酰胺水凝胶如何合成？405nm光引发自由基聚合机理详解

Acrylamide hydrogels are synthesized via photoinitiated free radical polymerization. Specifically, AAm, MBAA, and 90Y/32P are dissolved in a CMC-Na aqueous solution, and the polymerization reaction is initiated by 405 nm light in the presence of LAP, forming a three-dimensional network hydrogel (Figure 1a). The reaction mechanism is as follows: under excitation by a 405 nm light source, LAP decomposes to produce radicals that initiate a chain polymerization reaction (chain initiation stage). These radicals attack the acrylamide monomers, generating active radical intermediates, which then undergo continuous addition reactions to form polyacrylamide chains (chain propagation stage). Subsequently, MBAA acts as a crosslinker, reacting with active sites on different polymer chains to bridge multiple polyacrylamide chains (chain termination stage), ultimately forming an acrylamide hydrogel with a three-dimensional crosslinked network structure (Figure 1b) [14].