MICT与HIIT如何改善糖尿病小鼠代谢?10周运动干预效果对比

2026-02-07 MedSci xAi 发表于广东省
本研究探讨中等强度持续训练(MICT)与高强度间歇训练(HIIT)对db/db糖尿病小鼠体重和血糖的改善效果。实验显示两种运动方式均能从第4周显著降低体重,第6周起持续改善血糖水平,为糖尿病运动干预提供实证依据。
2. Effects of MICT and HIIT on General Conditions of db/db Mice (1) MICT and HIIT Reduce Body Weight in db/db Mice: Compared to the NC group, the body weight of mice in the DC group significantly increased from week 0 to week 10 (P < 0.001). Compared to the DC group, the body weight of mice in both the MICT and HIIT groups began to significantly decrease from week 4 (P < 0.05) and continued to significantly decrease from week 6 (P < 0.001). There was no significant difference in body weight between the MICT and HIIT groups. (2) MICT and HIIT Lower Random Blood Glucose Levels in db/db Mice: Compared to the NC group, the random blood glucose levels of mice in the DC group significantly increased from week 0 to week 10 (P < 0.001). Compared to the DC group, the blood glucose levels of mice in the MICT group significantly decreased from week 6 to week 8 (P < 0.05) and at week 10 (P < 0.01). Compared to the DC group, the blood glucose levels of mice in the HIIT group significantly decreased from week 6 to week 8 (P < 0.01) and at week 10 (P < 0.001). There was no significant difference in blood glucose levels between the MICT and HIIT groups during the 10-week intervention period.
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