Methods: The analgesic activity of LM49 was investigated using the acetic acid writhing test. The site of action for the analgesic effect of LM49 was explored using the hot plate test and the formalin test. The pain threshold was assessed using the tail flick test. The effect of LM49 on inflammatory pain was evaluated in a rat migraine model. The mechanism of action for the analgesic effects of LM49 was analyzed by adding tool drugs.
LM49镇痛活性研究：实验方法与机制分析
本文详解LM49化合物的镇痛活性研究方法，包括醋酸扭体实验、热板实验和福尔马林实验等经典模型，解析其在大鼠偏头痛模型中的作用机制及工具药物验证过程。
与梅斯小智对话
