Platinum-based drugs are widely used in the treatment of malignant tumors; however, platinum-based chemotherapy regimens can cause a series of adverse events (AEs) in patients, limiting their clinical application and reducing patients' quality of life. In recent years, with an increase in reports of muscle-related adverse reactions associated with platinum-based drugs, patients' quality of life has been affected to varying degrees. However, there is a lack of effective preventive and therapeutic strategies in clinical practice. Therefore, it is of great significance to conduct in-depth research and analysis on muscle-related adverse reactions caused by platinum-based drugs.