The leave-one-out analysis showed that, after sequentially removing individual SNPs, the combined effect estimates of the remaining SNPs remained consistent with the overall results (β range: -0.483 to -0.417, all P values < 0.05), indicating that the negative association between glutamine and late-onset myasthenia gravis risk is not driven by a single SNP, and the results are stable and reliable. The visualization in Figure 3 further confirms these findings.
留一法分析如何验证谷氨酰胺与重症肌无力的负相关稳定性？
本文通过留一法分析验证谷氨酰胺与迟发性重症肌无力的负相关稳定性，结果显示剔除单个SNP后组合效应估计值保持一致性（β范围：-0.483至-0.417），所有P值均小于0.05，证实结果不受单一SNP驱动且具有高度可靠性。
与梅斯小智对话
