Bu Xu Ping Chuan膏如何调节肠道菌群?有益菌增殖与代谢通路增强机制解析

昨天 MedSci xAi 发表于广东省
本文分析Bu Xu Ping Chuan膏对肠道有益菌群的影响,重点探讨Roseburia、Phascolarctobacterium和Parabacteroides的增长趋势及其与丁酸盐代谢通路的关联,揭示中药通过微生物结构微调实现抗炎和能量代谢调节的作用机制。

In terms of potentially beneficial bacteria, the abundance of Roseburia, Phascolarctobacterium, and Parabacteroides showed an increasing trend in the MPH group. Although the changes in abundance of these genera did not reach statistical significance (P > 0.05) in this study, their upward trend is consistent with the enhanced trend of the "butyrate metabolism pathway" observed in functional predictions (see 4.2.4). This suggests that even minor adjustments in microbial structure may have cumulative effects at the metabolic function level. Parabacteroides has direct anti-inflammatory and immune-regulatory capabilities and can inhibit key pro-inflammatory factors. Phascolarctobacterium produces acetate and propionate, which are involved in host energy metabolism regulation. The increasing trends of these genera suggest that Bu Xu Ping Chuan膏 (a traditional Chinese medicine) may improve the gut microenvironment by promoting the proliferation of beneficial bacteria.

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