The scatter plots in Figure 2 (A-D) illustrate the aforementioned causal relationships. Each point in the plots represents the effect of an SNP on the exposure and outcome, while the regression lines of different colors represent the fitting results of the IVW (Inverse Variance Weighted), MR-Egger, and weighted median methods. Figures 2A to 2D correspond to the analysis results for glutamine, citrulline, testosterone, and lactic acid, respectively, with the direction of each regression line consistent with the corresponding causal effect estimate.