PHENIX研究如何改变宫颈癌手术？2025 NEJM最新证据解读

The PHENIX study. Initial results were first presented at the ASCO Annual Meeting in June and the full text was published in The New England Journal of Medicine (N Engl J Med. 2025 Oct 16;393(15):1463-1474). For early-stage cervical cancer patients meeting specific criteria, sentinel lymph node biopsy alone is non-inferior to pelvic lymphadenectomy (combined with radical hysterectomy) in terms of survival outcomes, but with fewer surgical complications. This has the potential to rewrite global cervical cancer guidelines.