8. Analysis of the expression levels of cytoskeletal proteins F-actin and G-actin: Western blot results showed that compared to the Water group, the ratio of F-actin to G-actin in the hippocampal region of the EtOH group mice was significantly increased (P < 0.05, n = 5). After overexpression of ICAM5, the F-actin/G-actin ratio in the ICAM5 + EtOH group was significantly decreased compared to the EtOH group (P < 0.05, n = 5).
ICAM5过表达如何逆转乙醇诱导的海马F-actin/G-actin比率异常?Western blot实验解析
本研究通过Western blot技术分析乙醇暴露对小鼠海马区细胞骨架蛋白F-actin与G-actin表达比率的影响,发现ICAM5过表达可显著逆转乙醇诱导的F-actin/G-actin比率异常升高,为酒精性神经损伤的分子机制提供新见解。
与梅斯小智对话