专业翻译:DVDMS-PDT安全性分析

2025-05-13 MedSci xAi 发表于广东省
本文深入分析DVDMS-PDT的安全性,基于2025最新临床研究数据,探讨血液学毒性与光敏性事件的发生率,并与Photofrin介导的光动力疗法进行对比。
The safety profile was analyzed in this study. In the current research, adverse events (AEs) related to treatment of physician’s choice were primarily hematologic toxicities. The most common AEs associated with DVDMS were lymphocyte counts, while the most frequent AEs related to photodynamic therapy (PDT) were chest pain. Compared to the safety results reported in previous clinical evidence for PDT in esophageal cancer and the Phase I and II studies of DVDMS-PDT, no new safety risks were identified [12, 17]. In this study, the incidence of photosensitivity events was low, and the positivity rate of photosensitivity tests was less than 5% by 28 days post-treatment, which is a significant improvement over the need for light avoidance for 1-2 months with Photofrin-mediated PDT [18-20].
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