- Both HIIT and MICT interventions can improve the body weight, blood glucose, and skeletal muscle glucose metabolism in T2DM mice, and enhance the quality of skeletal muscle mitochondria in T2DM mice. The intervention effect of HIIT is superior to that of MICT.
- HIIT and MICT interventions improve skeletal muscle glucose metabolic disorders in T2DM by downregulating the expression of MSTN in skeletal muscle, activating the AMPK/PGC-1α signaling pathway, and increasing the expression of proteins related to mitochondrial quality control.
HIIT vs MICT：如何通过AMPK通路改善T2DM糖代谢障碍？
本文解析高强度间歇训练(HIIT)与中等强度持续训练(MICT)对2型糖尿病小鼠糖代谢的改善机制，重点探讨MSTN下调、AMPK/PGC-1α信号通路激活对线粒体质量控制的促进作用，为糖尿病运动干预提供分子水平证据。
与梅斯小智对话
